新型コロナウイルスの起源問題～RaTG13はフェイクか？～3

図3　キクガシラコウモリとセンザンコウのコロナウイルス、および、SARS-CoV-2のSタンパク・アミノ酸配列の比較（S2サブユニット）

0: LYRa11(2011), 1: CoV ZXC21(2015)、2: CoV ZC45(2017)、

3: PCoV GX-P1E(2017)、4: PCoV MP789(2019)、5: RaTG13(2013),

6: SARS-CoV-2 WIV02(2019)

686-720

0: NTDQKSIVAYTMSLGAENSIAYANNSIAIPTNFS

1: STGQKAIVAYTMSLGAENSIAYANNSIAIPTNFS

2: STSQKAIVAYTMSLGAENSIAYANNSIAIPTNFS

3: SVNQRSIIAYTMSLGAENSVAYSNNSIAIPTNFT

4: SVSSQAIIAYTMSLGAENSVAYANNSIAIPTNFT

5: SVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFT

6: SVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFT

721-760

0: ISITTEVMPVSMAKTSVDCTMYICGDSQECSNLLLQYGSF

1: ISVTTEVMPVSMAKTSVDCTMYICGDSIECSNLLLQYGSF

2: ISVTTEVMPVSMAKTSVDCTMYICGDSIECSNLLLQYGSF

3: ISVTTEILPVSMTKTSVDCTMYICGDSIECSNLLLQYGSF

4: ISVTTEILPVSMTKTSVDCTMYICGDSIECSNLLLQYGSF

5: ISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSF

6: ISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSF

761-800

0: CTQLNRALSGIAVEQDKNTQEVFAQVKQIYKTPAIKDFGG

1: CTQLNRALSGIAIEQDKNTQEVFAQVKQIYKTPPIKDFGG

2: CTQLNRALSGIAIEQDKNTQEVFAQVKQIYKTPPIKDFGG

3: CTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGG

4: CTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGG

5: CTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGG

6: CTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGG

801-840

0: FNFSQILPDPSKPTKRSFIEDLLFNKVTLADAGFMKQYGE

1: FNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGD

2: FNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGD

3: FNFLQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGD

4: FNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGD

5: FNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGD

6: FNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGD

841-880

0: CLGDISARDLICAQKFNGLTVLPPLLTDEMIAAYTAALVS

1: CLGDISARDLICAQKFNGLTVLPPLLTDEMIAAYTAALIS

2: CLGGISARDLICAQKFNGLTVLPPLLTDEMIAAYTAALIS

3: CLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLA

4: CLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLA

5: CLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLA

6: CLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLA

881-920

0: GTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYEN

1: GTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYEN

2: GTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYEN

3: GTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYEN

4: GTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYEN

5: GTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYEN

6: GTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYEN

921-960

0: QKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQAL

1: QKLIANQFNSAIGKIQESLTSTASALGKLQDVVNQNAQAL

2: QKLIANQFNSAIGKIQESLTSTASALGKLQDVVNQNAQAL

3: QKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQAL

4: QKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQAL

5: QKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQAL

6: QKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQAL

961-1000

0: NTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITG

1: NTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITG

2: NTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITG

3: NTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITG

4: NTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITG

5: NTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITG

6: NTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITG

1001-1040

0: RLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKR

1: RLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKR

2: RLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKR

3: RLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKR

4: RLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKR

5: RLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKR

6: RLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKR

1041-1080

0: VDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAP

1: VDFCGKGYHLMSFPQSAPHGVVFLHVTYIPSQEKNFTTAP

2: VDFCGKGYHLMSFPQSAPHGVVFLHVTYIPSQEKNFTTAP

3: VDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAP

4: VDFCGKGYHLMSFPQSAPHGVVFLHVTYVPSQEKNFTTTP

5: VDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAP

6: VDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAP

1081-1120

0: AICHEGKAYFPREGVFVSNGTSWFITQRNFFSPQLITTDN

1: AICHEGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDN

2: AICHEGKAHFPREGVFVSNGTHWFVTQRNFYEPKIITTDN

3: AICHEGKAHFPREGVFVSNGTHWFITQRNFYEPQIITTDN

4: AICHEGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDN

5: AICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDN

6: AICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDN

1121-1160

0: TFVSGNCDVVIGIINNTVYDPLQPELDSFKEELDKYFKNH

1: TFVSGNCDVVIGIINNTVYDPLQPELDSFKEELDKYFKNH

2: TFVSGNCDVVIGIINNTVYDPLQPELDSFKEELDKYFKNH

3: TFVSGSCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNH

4: TFVSGSCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNH

5: TFVSGSCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNH

6: TFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNH

1161-1200

0: TSPDVDLGDISRINASVVNIQKEIDRLNEVAKNLNESLID

1: TSPDIDLGDISGINASVVNIQKEIDRLNEVARNLNESLID

2: TSPDIDLGDISGINASVVNIQKEIDRLNEVARNLNESLID

3: TSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLID

4: TSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLID

5: TSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLID

6: TSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLID

1201-1240

0: LQELGKYEQYIKWPWYVWLGFIAGLIAIVMATILLCCMTS

1: LQELGKYEHYIKWPWYVWLGFIAGLIAIVMVTILLCCMTS

2: LQELGKYEQYIKWPWYVWLGFIAGLIAIVMVTILLCCMTS

3: LQELGKYEQYIKWPWYIWLGFIAGLIAIIMVTIMLCCMTS

4: LQELGKYEQYIKWPWYIWLGFIAGLIAIIMVTIMLCCMTS

5: LQELGKYEQYIKWPWYIWLGFIAGLIAIIMVTIMLCCMTS

6: LQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTS

1241-1274

0: CCSCLKGACSCGSCCKFDEDDSEPVLKGVKLHYT

1: CCSCLKGCCSCGFCCKFDEDDSEPVLKGVKLHYT

2: CCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT

3: CCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT

4: CCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT

5: CCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT

6: CCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT